nMutations that alter
the genes coding for growth factors.
ØMay
occur spontaneously
ØResult from
exposure to an carcinogen
Ø ( any substance that
increases the risk of caner.)
nUsually there is
more than one mutation.
nThere are two types
of genes that control cell division
ØProto-oncogens
ØTumor
suppressing genes (p53 gene)